EVALUATION OF DIHYDROPYRIMIDINASE-RELATED PROTEIN 2 IN THE HIGH-CLASS SPORTSMEN’S BLOOD AND SALIVA BEFORE COMPETITION

Abstract

The article concerns evaluation of the levels of dihydropyrimidinase-related protein 2 (DRP2) in the platelets and saliva and natural anti-DRP2 autoantibodies in the serum of the high-class sportsmen before competition beginning. The blood and saliva samples taken from the same sportsmen in quiet and relaxed state served as controls. Evaluation of the levels of DRP2 and natural antiDRP2 autoantibodies was carried out by indirect ELISA test on polysterene plates with moderate level of adsorption. The results indicate to noticeable down regulation of natural antiDRP2 autoantibodies in the serum (p < 0.01) and to lack of any changes of DRP2 levels in the platelets and saliva of these sportsmen before competition beginning. Basing on our earlier data, we come to a conclusion that the results reflects the similar changes of DRP2 level in the sportsmen’s brain subcortical structures and indicate to increase of their aggression level prior to competition beginning.