STUDY OF BIOCHEMICAL MECHANISMS OF FATIGUE AGAINST THE BACKGROUND OF PHYSICAL LOADS
Abstract
The influence of the effect of physical activity of various intensity on the content of glucose, lactic acid and uric acid, as well as on the content of free radical oxidation products (FRO) - hydroperoxides (HP) and malondialdehyde (MDA) in the blo-od of rats was studied. During the experiments, it was found that physical fatigue occurs against the background of an increased content of lactate and uric acid and a decrease in glucose levels, as well as intensification of lipid peroxidation processes, which can serve as a trigger for reducing the functional activity of body systems. It was also noted that fatigue caused by intense physical activity is accompanied by an intensification of anaerobic glycolysis, glucose deficiency and, as a result, an excessive increase in lactate.
References
Директива 2010/63/EU Европейского парламента и совета Европейского союза по охране животных, используемых в научных целях. СПб., 2012.
Каркищенко В.Н., Капанадзе Г.Д., Деньгина С.Е., Станкова Н.В. Разработка методики оценки физической выносливости мелких лабораторных животных для изучения адаптогенной активности некоторых лекарственных препаратов. Биомедицина, 2011, № 1, c. 72–74.
Полевщиков М.М., Солодков А.С. Особенности утомления и восстановления спортсменов. Ученые записки университета имени П. Ф. Лесгафта, 2013, № 6 (100), c. 130–143.
Солодков А.С. Физическая работоспособность спортсменов и общие принципы её коррекции (часть 1). Ученые записки университета им. П.Ф. Лесгафта, 2014, № 3 (109), c. 148–158.
Фудин, Н.А., Вагин Ю.Е., Пигарева С.Н. Системные механизмы утомления при физических нагрузках циклической направленности. Вестник новых медицинских технологий, 2014, Т. 21, № 3, c. 118–121.
Birrer D., Leinhard D., Williams C. et al. Prevalence of non-functional overreaching and the overtraining syndrome in Swiss elite athletes. Schweizerische Zeitschrift Für Sportmedizin Und Sporttraumatologie, 2013, vol. 61, № 4, p. 23–29.
Cardoos N. Overtraining syndrome. Curr. Sports Med. Rep, 2015, vol. 14, № 3, pp. 157–158.
Kellmann M. Bertollo M., Bosquet L. et al. Recovery and performance in sport: Consensus Statement. Int. J. Sports Physiol. Perform, 2018, vol. 13, № 2, p. 240–245.
Nieman D.C., Groen A.J., Pugachev A., Vacca G. Detection of Functional Overreaching in Endurance Athletes Using Proteomics. Proteomes, 2018, vol. 6, № 3, p. 33.
Schwellnus M., Soligard Т., Alonso J. M. et al. How much is too much? (Part 2) International Olympic Committee consensus statement on load in sport and risk of illness. Br. J. Sports Med, 2016, vol. 50, pp. 1043–1052.
Keywords
physical activity
intense physical activity
lipid peroxidation
lactic acid
glucose
uric acid
male rats спортсмен
физическая нагрузка
интенсивные физические нагрузки
перекисное окисление липидов
молочная кислота
мочевая кислота
глюкоза
самцы крыс idmançı
fiziki fəaliyyət
ifrat fiziki yüklənmə
lipidlərin perekisli oksidləşməsi
süd turşusu
sidik cövhəri
qlükoza
erkək siçovullar
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Most read articles by the same author(s)
- P.A. Shukurova, R.M. Guluzadeh, THE ROLE OF OXIDATIVE STRESS IN THE DEVELOPMENT OF OVERSTRAIN UNDER PHYSICAL ACTIVITY , Scientific News of Academy of Physical Education and Sport: Vol. 4 No. 2 (2022): SCIENTIFIC NEWS OF ACADEMY OF PHYSICAL EDUCATION AND SPORT